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Bridging The Gap: Molecular Cognition, Neuro-Economy, And The Reductionist Paradigm In Understanding Conscious Brain States
Issue Vol. 2 No. 01 (2025): VOLUME 02 ISSUE 01 --- Section Articles
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Abstract
This research article investigates the intersection of molecular cellular cognition, computational neuroscience, and the philosophical underpinnings of mind-brain reductionism. By synthesizing current understanding of immediate early gene expression, specifically the Arc gene, with the systemic default mode network fluctuations, the study explores how memory formation and conscious states emerge from a hierarchy of biological processes. The investigation addresses the "hard problem" of consciousness by contrasting David Chalmers’ non-reductionist views with the emerging "new kid in town"—molecular and cellular cognition (MCC). Methodologically, the paper employs a meta-analytical theoretical framework, examining existing data on cAMP-responsive element-binding protein (CREB) mutations and spontaneous low-frequency BOLD signal fluctuations in clinical populations, particularly those with schizophrenia. The findings suggest that while reductionism offers a powerful tool for mapping neuronal competition and selection, it must be balanced with an appreciation for the "economy of brain network organization." This economy dictates that neural systems prioritize cost-efficiency and functional integration, which reductionist models often overlook. The study concludes that an integrated "critical neuroscience" approach, which accounts for the body, environment, and social context, is necessary to move beyond the limitations of traditional physicalism.
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References
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