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European Journal of Emerging Real-Time IoT and Edge Infrastructures

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Federated Learning–Driven Intelligence for Autonomous and Medical Cyber-Physical Systems: Integrative Architectures, Privacy Preservation, and Deployment Challenges

1 Department of Electrical and Computer Engineering, University of Toronto, Canada

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Abstract

The rapid proliferation of data-intensive cyber-physical systems has fundamentally altered how intelligence is designed, trained, and deployed across domains such as autonomous transportation, smart healthcare, and medical image analysis. Traditional centralized machine learning paradigms, while historically dominant, increasingly face structural limitations related to privacy leakage, regulatory compliance, communication overhead, and domain heterogeneity. Federated learning has emerged as a transformative alternative that distributes model training across decentralized data silos while preserving local data ownership. This research article presents a comprehensive and theoretically grounded investigation into federated learning as an enabling intelligence paradigm for autonomous driving systems and medical imaging applications, with a particular emphasis on self-driving vehicles and brain tumor classification. Drawing on foundational surveys of autonomous vehicle intelligence (Badue et al., 2021) and hybrid deep learning models for medical diagnosis (Biswas & Islam, 2021; Biswas & Islam, 2023), the study situates federated learning within the broader evolution of machine learning architectures.

The article advances an integrative analytical framework that unifies insights from vehicular intelligence, Internet of Things infrastructures, medical imaging pipelines, and privacy-preserving computation. Rather than presenting experimental benchmarks, the study adopts an interpretive methodology grounded in cross-domain synthesis of existing empirical findings. The analysis elucidates how federated learning architectures address non-independent and identically distributed data, system heterogeneity, and adversarial vulnerabilities in both autonomous mobility and healthcare settings. Particular attention is given to hierarchical aggregation strategies, blockchain-enabled coordination, homomorphic encryption, and explainable artificial intelligence as mechanisms that enhance trust and robustness.

The results reveal that federated learning is not merely a technical optimization but a socio-technical reconfiguration of intelligence production, redistributing power, responsibility, and risk across stakeholders. In autonomous driving, federated learning enables collaborative perception and decision-making across fleets without compromising proprietary or personal data, complementing the perception-planning-control pipeline outlined in self-driving system surveys (Badue et al., 2021). In medical imaging, federated architectures support scalable diagnostic intelligence across institutions while mitigating ethical and legal barriers associated with centralized patient data repositories (Biswas & Islam, 2023). The discussion critically examines unresolved challenges, including convergence instability, communication efficiency, fairness, and regulatory alignment, and articulates a forward-looking research agenda that bridges engineering rigor with societal accountability.


Keywords

Federated learning, autonomous driving systems, medical image analysis

References

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How to Cite

Federated Learning–Driven Intelligence for Autonomous and Medical Cyber-Physical Systems: Integrative Architectures, Privacy Preservation, and Deployment Challenges. (2025). European Journal of Emerging Real-Time IoT and Edge Infrastructures, 2(01), 17-21. https://www.parthenonfrontiers.com/index.php/ejertiotei/article/view/494

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